The answer is not yet.

So far ClamWin does not have on-access scanner so you need to be careful and scan a suspicious file before opening it. If you do that you will be as safe as with a commercial antivirus. User awareness is sometimes better than automatic protection, as it may be easier to break the automatic protection than to fool an educated user.

However an average user with little knowledge about online and computer security the on-access component is a must and the ClamWin should be used only as a complimentary scanner. We are developing it and will release it in the next major version update.

If the "Integration with Windows Explorer" option is checked during installation, any file can be scanned from within Windows Explorer simply by right-clicking on it and selecting "Scan With ClamWin Free Antivirus"